![]() ![]() We concluded that BIS is valid for between-subject comparisons of body fluid compartments, is appropriate in clinical settings where change in ECV/ICV ratio is important, and should be used by comparing the required level of accuracy to the inherent technique error/variance. The correlation coefficients of dilution versus BIS volumes (r = 0.93 to 0.96) were significant at P < 0.0001 SEEs were: TBW, 2.23 L ECV, 1.26 L and ICV, 1.71 L. Intracellular homeostasis is maintained by shifts in water, solutes, and numerous other substances across the cell membrane. Intracellular fluid refers to the fluid that lies inside of the cell, sometimes referred to as cytoplasm, while extracellular fluid is the fluid that is found outside of the cells. The composition of ICF is very different from extracellular fluid (ECF) ( Fig. Intrinsic factors that dictate the movement of crystalloid fluids into individual body fluid compartments (intracellular, interstitial, intravascular) include the normal distribution of total body water, and the factors involved with the movement of fluids across the capillary membrane (e.g., transmembrane hydrostatic, colloid osmotic pressure. The total water composition in the human body constitutes 67 of intracellular fluid and 26 of extracellular fluid. The intracellular fluid (ICF) compartment comprises approximately 40 of body weight (approximately two thirds of total body water). The cytosol and the organelles and molecules contained within are referred. The fluid that is present inside the cells is called intracellular fluid. ![]() Intracellular fluid is often referred to as cytosol when discussing cellular functions. The intracellular fluid is therefore stored within the intracellular compartments of the body. Dilution measures (TBW, 51.00 +/- 9.30 ECV, 19.88 +/- 3.14 ICV, 31.12 +/- 6.80 L) and BIS volumes (TBW, 50.03 +/- 7.67 ECV, 20.95 +/- 3.33 ICV, 29.04 +/- 4.51 L) were significantly different for ECV (P < 0.01) and ICV (P < 0.05) some individual differences were large. Intracellular fluid is the fluid that exists within the cells of multi-celled organisms. An electrolyte is an element or compound that, when dissolved in a liquid, decomposes into ions. Solutes are electrolytes, which help keep the body working properly. Electrode placement, posture, exercise, food/fluid intake, and ambient temperature were controlled. This liquid contains water, proteins, and dissolved solutes. ![]() Impedance was measured (50-500 kHz) at rest, on a nonconducting surface, with a BIS analyzer. Thirteen healthy males (mean +/- SD: age, 23 +/- 3 yr body mass, 80.6 +/- 14.7 kg) had their TBW and ECV measured by ingesting dilution tracers (7.27 g deuterium oxide, 1.70 g sodium bromide blood samples at 0 and 4 h). The purpose of this study was to test the validity of a multiple frequency bioimpedance spectroscopy (BIS) technique that estimates extracellular fluid volume (ECV), intracellular fluid volume (ICV), and total body water (TBW). ![]()
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